Nystatin

Nystatin recalls: 6 FDA reports

Recalls involving Nystatin. What was wrong with each batch, and how the FDA graded the risk.

6Reports
0Class I
1Ongoing
2026-07-22Most recent

What the classes mean

The FDA sorts every recall into one of three classes. The class is the whole story. It is also the part people skip.

ClassWhat the FDA is saying
Class IThere is a reasonable probability that using this will cause serious harm or death.
Class IIIt may cause temporary or reversible harm. Serious harm is unlikely.
Class IIIIt breaks a rule but is unlikely to hurt anyone. Often a labelling fault.

Class II is the bulk of every list here. That matters. A long list of Class II says something different from one Class I.

By class

ClassReports
Class II5
Class III1

By year reported

YearReports
20181
20203
20211
20261
Checking whether it affects you

The lot or code number is what matters. Not the product name. A recall covers specific lots. Yours may not be one of them.

Check the code on your package against the report. The FDA keeps the current list at fda.gov/safety/recalls.

The reports

The text below is quoted from the FDA record word for word.

Nystatin Cream USP, (100,000 USP Nystatin Units), NET WT 15 g, Rx only, 15 g tube, Manufactured by Padagis, Ye

D-0677-2026  ·  Class II  ·  reported 2026-07-22  ·  Ongoing

Why it was recalled
Subpotent Drug: Low out of specification assay results performed during long-term stability testing.
Product
Nystatin Cream USP, (100,000 USP Nystatin Units), NET WT 15 g, Rx only, 15 g tube, Manufactured by Padagis, Yeruham, Israel, NDC 45802-059-35
Where it went
USA Nationwide
How much
180,936 tubes

Nystatin Oral Suspension, USP 100,000 units per mL, Cherry/Peppermint Flavor, Rx ONLY, packaged in a) 16 fl o

D-0721-2021  ·  Class II  ·  reported 2021-08-18  ·  Terminated

Why it was recalled
Lack of CGMP: This recall is being carried out due to potential for carry over of Senna Syrup.
Product
Nystatin Oral Suspension, USP 100,000 units per mL, Cherry/Peppermint Flavor, Rx ONLY, packaged in a) 16 fl oz (473 mL) NDC 0121-0868-16; b) 2 fl oz (60 mL) NDC 0121-0868-02; Manufactured by: Pharmaceutical Associates, Inc. Greenville, SC 29605
Where it went
Distributed Nationwide in the USA
How much
a) 1002 cases (12 bottles/case); b) 458 cases (24 bottles/case)

Nystatin Oral Suspension, USP 100,000 units per mL, Cherry/Peppermint Flavor, 16 fl. oz. (473 mL), Rx only, Ph

D-1494-2020  ·  Class II  ·  reported 2020-08-19  ·  Terminated

Why it was recalled
Subpotent drug: Out of specification for assay at the 15-month test interval.
Product
Nystatin Oral Suspension, USP 100,000 units per mL, Cherry/Peppermint Flavor, 16 fl. oz. (473 mL), Rx only, Pharmaceutical Associates, Inc. Greenville, SC 29605, NDC 0121-0810-16
Where it went
Nationwide USA
How much
7416 bottles

Nystatin Oral Suspension, USP, 100,000 units per mL, Cherry/Peppermint Flavor, 16 fl oz (473 mL) bottle, Rx ON

D-1060-2020  ·  Class II  ·  reported 2020-04-01  ·  Terminated

Why it was recalled
SubPotent Drug: Low out-of-specification results for assay testing.
Product
Nystatin Oral Suspension, USP, 100,000 units per mL, Cherry/Peppermint Flavor, 16 fl oz (473 mL) bottle, Rx ONLY, pai Pharmaceutical Associates, Inc., Greenville, SC 29605; NDC 0121-0810-16.
Where it went
Nationwide in the USA.
How much
7416 bottles

Nystatin Oral Suspension, USP 100,000 units per mL Cherry/Peppermint Flavor, 16 fl oz (473 mL) Rx Only, pai,

D-0824-2020  ·  Class II  ·  reported 2020-02-05  ·  Terminated

Why it was recalled
Subpotent: Out of specification for assay at the 12-month time point.
Product
Nystatin Oral Suspension, USP 100,000 units per mL Cherry/Peppermint Flavor, 16 fl oz (473 mL) Rx Only, pai, Pharmaceutical Associates, Inc. Greenville, SC 29605. NDC 0121-0810-16
Where it went
Distributed Nationwide in the US
How much
6288 16 oz bottles

Nystatin Oral Suspension, USP, 500,000 units/5 mL, For Institutional Use Only, packaged in 5 mL cups, Rx Only

D-0865-2018  ·  Class III  ·  reported 2018-06-13  ·  Terminated

Why it was recalled
Resuspension problems: Out of specification for appearance and resuspendability.
Product
Nystatin Oral Suspension, USP, 500,000 units/5 mL, For Institutional Use Only, packaged in 5 mL cups, Rx Only, Pharmaceutical Associates, Inc. Greenville, SC 29605, NDC 0121-4810-05
Where it went
Nationwide
How much
275400 cups
Read these counts with three things in mind

A firm with more recalls usually makes more products. A contract packer runs hundreds of lines. It will out-recall a company with one product whatever either does. This is not a safety ranking.

Most recalls here are voluntary. A firm found its own fault and pulled the stock. That is the system working. It lands in this database looking the same as a recall the FDA had to push for.

Terminated means the FDA considers the recall finished. It is not a verdict. It does not mean anyone was harmed.

Source: openFDA enforcement reports, retrieved 2026-08-05. FDA dataset last updated 2026-07-29.

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