Divalproex Sodium

Divalproex Sodium recalls: 8 FDA reports

Recalls involving Divalproex Sodium. What was wrong with each batch, and how the FDA graded the risk.

8Reports
0Class I
0Ongoing
2024-04-03Most recent

What the classes mean

The FDA sorts every recall into one of three classes. The class is the whole story. It is also the part people skip.

ClassWhat the FDA is saying
Class IThere is a reasonable probability that using this will cause serious harm or death.
Class IIIt may cause temporary or reversible harm. Serious harm is unlikely.
Class IIIIt breaks a rule but is unlikely to hurt anyone. Often a labelling fault.

Class II is the bulk of every list here. That matters. A long list of Class II says something different from one Class I.

By class

ClassReports
Class II8

By year reported

YearReports
20152
20181
20192
20222
20241
Checking whether it affects you

The lot or code number is what matters. Not the product name. A recall covers specific lots. Yours may not be one of them.

Check the code on your package against the report. The FDA keeps the current list at fda.gov/safety/recalls.

The reports

The text below is quoted from the FDA record word for word.

Divalproex Sodium Extended-release Tablets, USP 250 mg, Rx Only, 100 tablets, Manufactured by: Amneal Pharmace

D-0426-2024  ·  Class II  ·  reported 2024-04-03  ·  Terminated

Why it was recalled
Failed dissolution specifications
Product
Divalproex Sodium Extended-release Tablets, USP 250 mg, Rx Only, 100 tablets, Manufactured by: Amneal Pharmaceuticals Pvt. Ltd. Ahmedabad, INDIA, Distributed by: Amneal Pharmaceuticals LLC, Bridgewater, NJ 08807, NDC 65162-755-10. NDC# 65162-755-10
Where it went
Product was distributed nationwide.
How much
21,452/100 count bottles

Divalproex Sodium Extended Release Tablets, USP, 250 mg, packaged in 100-count bottle, Rx only, Manufactured b

D-1362-2022  ·  Class II  ·  reported 2022-08-31  ·  Terminated

Why it was recalled
Failed dissolution specifications.
Product
Divalproex Sodium Extended Release Tablets, USP, 250 mg, packaged in 100-count bottle, Rx only, Manufactured by: Amneal Pharmaceuticals, India, Distributed by: Amneal Pharmaceuticals, Bridgewater, NJ, NDC 65162-755-10
Where it went
USA nationwide
How much
4,309 bottles

Divalproex Sodium Delayed-Release Tablets, USP 500mg, Rx Only, 100 Tablets, Distributed by: Sun Pharmaceutical

D-1291-2022  ·  Class II  ·  reported 2022-08-03  ·  Terminated

Why it was recalled
Failed Dissolution Specifications: Failure occurred during routine stability testing of dissolution test.
Product
Divalproex Sodium Delayed-Release Tablets, USP 500mg, Rx Only, 100 Tablets, Distributed by: Sun Pharmaceutical Industries, Inc., Cranbury, NJ 08512, Manufactured by: Sun Pharmaceutical Industries, Ltd., Halol-Baroda Highway, Halol- 389 350, Gujarat, India, NDC 62756-798-88.
Where it went
Nationwide in the USA
How much
9552 bottles

DIVALPROEX SODIUM EXTENDED-RELEASE TABLETS, USP Tablets, 250 mg, 100 count-unit dose carton, RX only, Manufact

D-1583-2019  ·  Class II  ·  reported 2019-08-07  ·  Terminated

Why it was recalled
cGMP deviations: Product was exposed above 50% relative humidity levels during packaging operations.
Product
DIVALPROEX SODIUM EXTENDED-RELEASE TABLETS, USP Tablets, 250 mg, 100 count-unit dose carton, RX only, Manufactured by Dr. Reddy's Laboratories Ltd. Bachupally - 500 090 India. Distributed by: Major Pharmaceuticals 17177 N Laurel Park Dr., Suite 233 Livonia, MI 48152. NDC # 0904-6363-61.
Where it went
Nationwide in the USA
How much
828 100-count unit dose cartons

Divalproex Sodium Extended-release Tablets, USP 250 mg, 100-count bottle, Rx only, Mfd.By: Dr. Reddy's Laborat

D-0507-2019  ·  Class II  ·  reported 2019-02-27  ·  Terminated

Why it was recalled
Failed Dissolution Specifications: Out of specification results observed for high dissolution.
Product
Divalproex Sodium Extended-release Tablets, USP 250 mg, 100-count bottle, Rx only, Mfd.By: Dr. Reddy's Laboratories Limited Bachupally - 500 090 India NDC 55111-533-01
Where it went
U.S.A. Nationwide
How much
10,656 bottles

Divalproex Sodium Delayed Release Tablets USP, 500 mg, 100-count bottle, RX Only, Manufactured by: Unichem Lab

D-0228-2018  ·  Class II  ·  reported 2018-01-24  ·  Terminated

Why it was recalled
Cross Contamination With Other Products: metronidazole powder was found in one bottle of Divalproex Sodium.
Product
Divalproex Sodium Delayed Release Tablets USP, 500 mg, 100-count bottle, RX Only, Manufactured by: Unichem Laboratories Ltd. Ind. Area, Meerut Road, Ghaziabad-201 003, India. Marketed By: Unichem Pharmaceuticals (USA), Inc. Hasbrouck Heights, NJ 07604. NDC 29300-140-01
Where it went
Product was distributed nationwide in the USA.
How much
96,876 Bottles of 30s

Divalproex Sodium Extended-Release Tablets, USP, 500 mg, 100 count bottles, Rx Only, Mfd. By. Dr. Reddy's Lab

D-1136-2015  ·  Class II  ·  reported 2015-06-24  ·  Terminated

Why it was recalled
Failed Dissolution Specifications; exceeded specification at the 9 hour time point
Product
Divalproex Sodium Extended-Release Tablets, USP, 500 mg, 100 count bottles, Rx Only, Mfd. By. Dr. Reddy's Laboratories Limited Bachupally 500 090 India --- NDC 55111-534-01
Where it went
Nationwide
How much
5,160 bottles

Divalproex Sodium Extended-Release Tablets, USP, (valproic acid activity), 250 mg, 100 count (NDC 55111-533-01

D-1135-2015  ·  Class II  ·  reported 2015-06-24  ·  Terminated

Why it was recalled
Failed Dissolution Specifications; exceeded specification at the 9 hour time point
Product
Divalproex Sodium Extended-Release Tablets, USP, (valproic acid activity), 250 mg, 100 count (NDC 55111-533-01) and 500 count (NDC 55111-533-05) bottles, Rx Only, Mfd. By. Dr. Reddy's Laboratories Limited, Bachupally 500 090 India
Where it went
Nationwide
How much
100 count 7479; 500 count - 2544
Read these counts with three things in mind

A firm with more recalls usually makes more products. A contract packer runs hundreds of lines. It will out-recall a company with one product whatever either does. This is not a safety ranking.

Most recalls here are voluntary. A firm found its own fault and pulled the stock. That is the system working. It lands in this database looking the same as a recall the FDA had to push for.

Terminated means the FDA considers the recall finished. It is not a verdict. It does not mean anyone was harmed.

Source: openFDA enforcement reports, retrieved 2026-08-05. FDA dataset last updated 2026-07-29.

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